Clodrosome is usually dosed intravenously to mice and rats in a relatively large volume, or about 1% of their body weight. This, along with the fact that the Clodrosome suspension is slightly more viscous than water, increases the possibility of adverse reactions due to improper injection techniques. When injecting Clodrosome intravenously, the following guidelines will limit the potential for adverse reactions, including death. If the technician performing the injections is unfamiliar with injecting larger volumes (≥1% of the animals body weight) and/or viscous suspensions, it is useful for the technician to practice on non-experimental animals prior to initiation of the experimental protocol. Extra animals should be on hand should animals demonstrate suspicious behavior during or after Clodrosome treatment.